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KMID : 0363620160370010090
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Journal of Korean Oriental Medicine
2016 Volume.37 No. 1 p.90 ~ p.100
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The Effect of Jeokbaekhaogwanjung-tang Herbal Acupuncture Solution on the Immune Activity of Spleen Cells of Aged Rats
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Lee Hyun-Suk
Choi Kang-Min
Yim Yun-Kyoung
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Abstract
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Objectives: The purpose of this study was to investigate the effect of Jeokbaekhaogwanjung-tang (JGT) distillate on
the immune activity of spleen cells of aged rats.
Methods: Spleen cells of 10w, 52w 72w old SD rats were cultured and treated with JGT distillate and the levels
of IL-2, IL-4, IL-10 and IFN-γ were measured.
Results: 1. The levels of IL-2 and IFN-γ in the spleen cells of 52w old rats were significantly decreased by JGT treatment.
2. The level of IFN-γ in the spleen cells of 72w old rats were significantly decreased by JGT treatment.
Conclusion: These results suggest that Jeokbaekhaogwanjung-tang distillate has an immune regulative effect by way
of suppressing the change of immune activity caused by aging in rats.
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KEYWORD
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Jeokbaekhaogwanjung-tang, immune activity, spleen cells, cytokine, aged rats
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